Surgery or drugs? new trial tackles tough Crohn's decision
NCT ID NCT05421455
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether early surgery or waiting and trying biologic drugs first is better for people with Crohn's disease who have bowel blockages. About 138 participants will be randomly assigned to either have surgery soon or receive biologic therapy. The goal is to see which approach leads to better symptom control and quality of life within one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
biologics
What this could lead to
If this trial succeeds, it could help doctors decide whether to operate early or try medications first for Crohn's-related bowel blockages.
What could go wrong
This is a single-center trial with only 138 participants, so results may not apply to everyone. Both treatments have risks, and the best approach may vary by patient.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of General Surgery, Jinling hosptal,Medical School of Nanjing University
RECRUITINGNanjing, Jiangsu, 210002, China
Contact Phone: •••-•••-•••• Email: •••••@•••••