Surgery or drugs? new trial tackles tough Crohn's decision
NCT ID NCT05421455
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times
Summary
This study looks at whether early surgery or waiting and trying biologic drugs first is better for people with Crohn's disease who have bowel blockages. About 138 participants will be randomly assigned to either have surgery soon or receive biologic therapy. The goal is to see which approach leads to better symptom control and quality of life within one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- biologics
- What this could lead to
- If this trial succeeds, it could help doctors decide whether to operate early or try medications first for Crohn's-related bowel blockages.
- What could go wrong
- This is a single-center trial with only 138 participants, so results may not apply to everyone. Both treatments have risks, and the best approach may vary by patient.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of General Surgery, Jinling hosptal,Medical School of Nanjing University
RECRUITINGNanjing, Jiangsu, 210002, China
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