Could a common heartburn drug shield kidneys after trauma?
NCT ID NCT06531642
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether giving the acid-reducing drug pantoprazole (Protonix) early after a traumatic injury with severe bleeding can lower the risk of acute kidney injury. Researchers will compare early dosing (within 2 hours of arrival) to usual timing (in the ICU) in 100 adult trauma patients. They will measure kidney injury markers and track kidney function for up to 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pantoprazole (Protonix)
What this could lead to
If it works, this could show that giving pantoprazole early after trauma helps prevent kidney damage in patients with severe bleeding.
What could go wrong
This is a small, early-phase trial (Phase 2/3) with only 100 patients, so results may not apply to everyone. The main goal is to check kidney injury markers, not long-term outcomes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Memorial Hermann Texas Medical Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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