Scientists track hearing decline in adults with genetic mutation

NCT ID NCT06354010

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at adults aged 30 to 55 who have hearing loss that started after age 16 and carry a mutation in the GJB2 gene. Researchers will track how their hearing changes over time using hearing tests and genetic analysis. The goal is to better understand this form of hearing loss, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict how hearing loss progresses in people with GJB2 mutations, leading to earlier or more personalized care.
What could go wrong
This is an observational study, not a treatment trial. It will not test any drug or therapy, so it cannot directly improve hearing. Results may not apply to people without GJB2 mutations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Deafness Hearing Loss, Sensorineural presbycusis sensorineural hearing loss disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Gui de Chauliac

    RECRUITING

    Montpellier, 34295, France

  • The University of South Florida Board of Trustees

    RECRUITING

    Tampa, Florida, 33620, United States

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