New heart attack treatment aims to stop the next one

NCT ID NCT05284747

Ongoing Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This study is testing if giving a cholesterol-lowering drug called evolocumab very early after a heart attack, along with standard care, is better than standard care alone at preventing future serious heart problems. It involves over 6,000 adults who were hospitalized for a heart attack. The goal is to see if this early treatment can reduce the risk of having another heart attack, a stroke, needing another heart procedure, or dying.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Advanced Cardiology Associates

Rochester Hills, Michigan, 48307, United States
Advanced Heart Care LLC

Bridgewater, New Jersey, 08807, United States
AdventHealth Orlando

Orlando, Florida, 32803, United States
Advocate Lutheran General Hospital

Park Ridge, Illinois, 60068, United States
Akademiska Sjukhuset i Uppsala

Uppsala, 751 85, Sweden
Alingsas Lasarett

Alingsås, 441 33, Sweden
Ascension Sacred Heart

Pensacola, Florida, 32504, United States
Ascension Saint John Bartlesville

Tulsa, Oklahoma, 74104, United States
Ascension Saint John Tulsa

Tulsa, Oklahoma, 74104, United States
Ascension Saint Thomas Nashville

Nashville, Tennessee, 37205, United States
Ascension Saint Vincent Heart Center

Indianapolis, Indiana, 46290, United States
Ascension Texas Cardiovascular

Austin, Texas, 78705, United States
Ascension Texas Cardiovascular Kyle

Kyle, Texas, 78640, United States
Aultman Hospital

Canton, Ohio, 44710, United States
Aurora Saint Lukes Medical Center

Milwaukee, Wisconsin, 53215, United States
Baptist Health Care

Pensacola, Florida, 32501, United States
Blekingesjukhuset Karlskrona

Karlskrona, 371 85, Sweden
Bon Secours St Marys Hospital Richmond

Midlothian, Virginia, 23114, United States
Bridgeport Hospital

Bridgeport, Connecticut, 06610, United States
Cardiology Associates of Fairfield County PC

Stamford, Connecticut, 06905, United States
Cardiology Associates of North Mississippi

Tupelo, Mississippi, 38801, United States
Cardiology Partners Clinical Research Institute

Palm Beach Gardens, Florida, 33410, United States
Cardiovascular Research of Knoxville North Knoxville Medical Center

Powell, Tennessee, 37849, United States
Centrallasarettet Vaxjo

Vaxjo, 351 85, Sweden
Centro de Pesquisa Clinica do Coracao

Aracaju, Sergipe, 49055-530, Brazil
Centro de Pesquisa Clínica Associação Hospitalar Moinhos de Vento

Porto Alegre, Rio Grande do Sul, 90035-001, Brazil
Chippenham Hospital

Richmond, Virginia, 23225, United States
Clearwater Cardiovascular Consultants

Clearwater, Florida, 33756, United States
Clearwater Cardiovascular Consultants

Safety Harbor, Florida, 34695, United States
Clinical Site Partners Orlando dba Flourish Research

Winter Park, Florida, 32789, United States
Clínica Silvestre Sante

Rio Branco, Acre, 69900785, Brazil
Cmep-Centro Multidisciplinar Ensino e Pesq

Joinville, Santa Catarina, 89204-250, Brazil
Eastern Shore Research Institute

Fairhope, Alabama, 36532, United States
Essentia Health Saint Marys Medical Center

Duluth, Minnesota, 55805, United States
Excel Medical Clinical Trials

Boca Raton, Florida, 33434, United States
Gavle Sjukhus

Gävle, 801 88, Sweden
Genesis Healthcare System

Zanesville, Ohio, 43701, United States
Great Lakes Clinical Trials - Ravenswood

Chicago, Illinois, 60640, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Hartford Hospital

Hartford, Connecticut, 06106, United States
Healthy Heart Cardiology

Grand Rapids, Michigan, 49546, United States
Heart Center Research LLC

Huntsville, Alabama, 35801-4317, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Hospital Beneficência Portuguesa

São Paulo, Rio Grande do Sul, 01323-900, Brazil
Hospital Israelita Albert Einstein

São Paulo, 05652-900, Brazil
Hospital Madre Teresa

Belo Horizonte, Minas Gerais, 30140-073, Brazil
Hospital Mãe de Deus

Porto Alegre, Rio Grande do Sul, 90840-440, Brazil
Hospital Regional de Presidente Prudente

Presidente Prudente, São Paulo, 19050-680, Brazil
Hospital Ruy Azeredo

Ipiranga Goiânia, Goiás, 74453-200, Brazil
Hospital Universitario Sao Francisco na Providencia de Deus

Ipiranga Goiânia, Goiás, 74453-200, Brazil
Hospital Universitário Ciências Médicas de Belo Horizonte

Belo Horizonte, Minas Gerais, 30140-073, Brazil
Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Hospital do Coracao de Pocos de Caldas CEC servicos medicos

Poços de Caldas, Minas Gerais, 37706-106, Brazil
Hudson Valley Cardiovascular Practice PC

Poughkeepsie, New York, 12601, United States
Instituto Atena de Pesquisa Clínica

Natal, Rio Grande do Norte, 59020-500, Brazil
Instituto Cardiovascular de Linhares

Linhares, Espírito Santo, 29900010, Brazil
Instituto Dante Pazanesse

São Paulo, São Paulo, 04012-909, Brazil
Instituto de Cardiologia de Santa Catarina

Praia Comprida, Sao Jose, Santa Catarina, 88103-450, Brazil
Instituto de Cardiologia do Rio Grande do Sul

Porto Alegre, Rio Grande do Sul, 90620-001, Brazil
Instituto de Pesquisa Clínica de Campinas

Campinas, São Paulo, 13060-080, Brazil
Instituto do coracao da Faculdade de Medicina da Universidade de Sao Paulo - InCor

São Paulo, 05403-000, Brazil
Irmandade da Santa Casa de Misericordia de Marilia

Marília, São Paulo, 90840-440, Brazil
Jackson Heart

Jackson, Mississippi, 39216, United States
Jesse Brown Veterans Affairs Medical Center

Chicago, Illinois, 60612, United States
John Muir Health and Cardiovascular Institute

Concord, California, 94520, United States
Kent Hospital

Warwick, Rhode Island, 02886, United States
Lancaster General Hospital/The Heart Group of Lancaster

Lancaster, Pennsylvania, 17603, United States
Lanssjukhuset Ryhov

Jönköping, 553 05, Sweden
Linkoping University Hospital

Linköping, 581 85, Sweden
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
McLaren Macomb Research Services

Mount Clemens, Michigan, 48043, United States
McLaren Northern Michigan Hospital

Petoskey, Michigan, 49770, United States
Midwest Heart and Vascular Specialists

Overland Park, Kansas, 66211, United States
Molndals Sjukhus

Molndahl, 431 80, Sweden
Montefiore Medical Center

The Bronx, New York, 10580, United States
Moses H Cone Memorial Hospital

Greensboro, North Carolina, 27401, United States
New York Presbyterian-Weill Cornell Medical Center

New York, New York, 10065, United States
North Kansas City Hospital

North Kansas City, Missouri, 64116, United States
Northern Arizona Healthcare Corporation Cardiovascular Institute

Flagstaff, Arizona, 86001, United States
Novant Health Heart and Vascular Institute Presbyterian Medical Center

Charlotte, North Carolina, 28204, United States
Ostersunds sjukhus

Östersund, 831 83, Sweden
Parkway Cardiology Associates

Oak Ridge, Tennessee, 37830, United States
Pima Heart and Vascular Clinical Research

Tucson, Arizona, 85719, United States
Prisma Upstate and Midlands Greenville Hospital System

Columbia, South Carolina, 29203, United States
Ps Cardiologico de PE - Procape

Casa Forte, Pernambuco, 52061-540, Brazil
Reading Hospital Tower Health

West Reading, Pennsylvania, 19611, United States
Reid Physician Associates

Richmond, Indiana, 47374, United States
Rhode Island Hospital

Providence, Rhode Island, 02903, United States
Richmond University Medical Center

Staten Island, New York, 10310, United States
Saint Lukes Boise Medical Center

Boise, Idaho, 83712, United States
Saint Lukes Hospital of Kansas City

Kansas City, Missouri, 64111, United States
Saint Michaels Medical Center

Newark, New Jersey, 07102, United States
Santa Casa de Porto Alegre

Porto Alegre, Rio Grande do Sul, 90620-001, Brazil
Scottsdale Healthcare at Shea - HonorHealth

Scottsdale, Arizona, 85258, United States
Skane Universitetssjukhus i Lund

Lund, 221 85, Sweden
Sodersjukhuset

Stockholm, 118 83, Sweden
South Shore University Hospital Northwell Health

Bay Shore, New York, 11706, United States
Sparrow Clinical Research Institute

Lansing, Michigan, 48912, United States
Stony Brook Medicine

Stony Brook, New York, 11794, United States
Sunderby Sjukhus

Luleå, 971 80, Sweden
Sundsvalls Sjukhus

Sundsvall, 851 86, Sweden
Tampa Cardiovascular Interventions and Research

Tampa, Florida, 33614, United States
Tennova Healthcare-Turkey Creek Medical Center

Knoxville, Tennessee, 37934, United States
The Ohio State University Wexner Medical Center

Columbus, Ohio, 43210, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of California Los Angeles

Los Angeles, California, 90095, United States
University of California-Irvine

Orange, California, 92868, United States
University of Colorado Hospital

Aurora, Colorado, 80045, United States
University of Florida and Shands Hospital

Jacksonville, Florida, 32209, United States
University of Florida at Gainesville

Gainesville, Florida, 32610, United States
University of Kansas Hospital

Kansas City, Kansas, 66160, United States
University of Louisville Health - Jewish Hospital

Louisville, Kentucky, 40202, United States
University of North Carolina Cardiology

Chapel Hill, North Carolina, 27599, United States
University of Rochester Medical Center

Rochester, New York, 14642, United States
Upstate Cardiology

Greenville, South Carolina, 29607, United States
VA Greater Los Angeles Healthcare System

Los Angeles, California, 90073, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232-8802, United States
Vastmanlands Sjukhus Vasteras

Västerås, 721 89, Sweden
Vrinnevisjukhuset, Norrkoeping

Norrköping, 601 82, Sweden
Wellspan Chambersburg Hospital

Chambersburg, Pennsylvania, 17201, United States

Conditions

Explore the condition pages connected to this study.

CARDIOVASCULAR DISEASE CORONARY REVASCULARIZATION MYOCARDIAL INFARCTION STROKE