Brain scans may predict who will respond to psychosis treatment

NCT ID NCT02670447

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether MRI brain scans can help predict which patients having their first psychotic episode will not respond to standard treatment. Researchers will scan 80 people aged 18-35 with schizophrenia or related disorders who have never taken antipsychotic medication. The goal is to see if certain brain markers can identify non-responders by the third month of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MRI (Magnetic Resonance Imaging)

What this could lead to

If successful, this could help doctors identify non-responding patients earlier, allowing for faster adjustments in treatment.

What could go wrong

This is a small, early-stage study (80 participants) focused on observation, not treatment. The MRI markers may not prove reliable enough for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizoaffective disorder schizophrenia schizophreniform disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chu Clermont-Ferrand

    NOT_YET_RECRUITING

    Clermont-Ferrand, 63003, France

    Contact

    Contact

  • Chu Grenoble

    NOT_YET_RECRUITING

    Grenoble, 38000, France

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    Contact

    Contact

  • Chu Le Vinatier

    NOT_YET_RECRUITING

    Bron, 69500, France

    Contact

    Contact

    Contact

  • Chu Saint Etienne

    RECRUITING

    Saint-Etienne, 42100, France

    Contact

    Contact

    Contact

    Contact

    Contact

  • HÔPITAL Edouard Herriot

    NOT_YET_RECRUITING

    Lyon, 69003, France

    Contact

    Contact