Flavor test: do fruit, tobacco, or menthol e-cigs help smokers quit?

NCT ID NCT06264154

First seen Nov 10, 2025 · Last updated Jun 22, 2026 · Updated 28 times

Summary

This study looks at whether the flavor of e-cigarettes affects how likely smokers are to switch from regular cigarettes to e-cigarettes. About 210 smokers who have tried to quit before will be given either fruit, tobacco, or menthol flavored e-cigarettes to use for 6 weeks. Researchers will track how many cigarettes they smoke and how satisfying they find the e-cigarettes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

e-cigarettes with flavored nicotine pods (fruit, tobacco, or menthol)

What this could lead to

If successful, this could show which e-cigarette flavor best helps smokers switch away from combustible cigarettes, potentially guiding future smoking reduction strategies.

What could go wrong

This is an early-stage observational study, not a treatment trial. Results may not apply to all smokers, and e-cigarettes carry their own health risks.

Conditions

The condition(s) this trial relates to.

Cigarette Smoking Smoking Tobacco Use Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.