New hope for urban youth: drug may cut asthma attacks

NCT ID NCT05347771

First seen Jan 22, 2026 · Last updated May 08, 2026 · Updated 12 times

Summary

This study tests whether the drug dupilumab can help prevent asthma attacks in children and teenagers aged 6 to 17 who live in urban areas and have frequent asthma problems. About 240 participants will receive either dupilumab or a placebo for one year, and researchers will count how many asthma attacks occur. The goal is to see if this treatment can reduce serious breathing emergencies in a high-risk group.

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Contacts and locations

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago: Division of Allergy and Immunology

    Chicago, Illinois, 60611, United States

  • Boston Children's Hospital: Department of Immunology

    Boston, Massachusetts, 02215, United States

  • Children's Hospital Colorado: Allergy Program

    Aurora, Colorado, 80045, United States

  • Children's National Medical Center: Children's Research Institute

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center: Asthma Center

    Cincinnati, Ohio, 45229, United States

  • Columbia University Medical Center: Division of Pediatric Pulmonology

    New York, New York, 10032, United States

  • Icahn School of Medicine at Mount Sinai: Division of Clinical Immunology, Immunology Institute

    New York, New York, 10029, United States

  • Washington University at St. Louis

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.