New pill shows promise for untreated brain tumors

NCT ID NCT04458272

First seen Apr 22, 2026 · Last updated May 14, 2026 · Updated 4 times

Summary

This study tests a new drug, DS-1001b, in 25 people with a slow-growing brain tumor (grade II glioma) that has a specific gene change (IDH1 mutation). Participants have not had chemotherapy or radiation before. The goal is to see if the drug can shrink the tumor and how safe it is.

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Contacts and locations

Locations

  • Hiroshima University Hospital

    Hiroshima, Japan

  • Kitasato University Hospital

    Sagamihara, Kanagawa, Japan

  • Kumamoto University Hospital

    Kumamoto, Japan

  • Kyorin University Hospital

    Tokyo, Japan

  • Kyoto University Hospital

    Kyoto, Japan

  • Nagoya University Hospital

    Nagoya, Aichi-ken, Japan

  • National Cancer Center Hospital

    Tokyo, Japan

  • National Hospital Organization Osaka National Hospital

    Osaka, Japan

  • Saitama Medical University International Medical Center

    Hidaka, Saitama, Japan

  • Tohoku University Hospital

    Sendai, Miyagi, Japan

  • Tokyo Women's Medical University Hospital

    Tokyo, Japan

Conditions

Explore the condition pages connected to this study.