Balloon treatment aims to defuse 'Time Bomb' plaques in heart arteries
NCT ID NCT04765956
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a drug-coated balloon can stabilize fatty plaques in heart arteries that are at risk of rupturing and causing a heart attack. Researchers treated 45 patients with a recent heart condition, using a special balloon to deliver medication directly to the plaque. The goal was to see if the plaque becomes less dangerous over 9 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
drug-eluting balloon (a balloon coated with an antiproliferative drug)
What this could lead to
If it works, this could point toward a way to treat vulnerable plaques before they cause a heart attack, potentially reducing future cardiac events.
What could go wrong
This is a small, early-phase trial with only 45 participants and no control group, so results may not apply broadly. The treatment itself carries risks like artery dissection or need for emergency stenting.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
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Contacts and locations
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Locations
-
Amsterdam UMC, location AMC
Amsterdam, 1105AZ, Netherlands