New pill could boost breathing in COPD patients already on inhalers
NCT ID NCT04238221
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding the drug doxofylline to standard inhaler therapy can improve lung function in people with stable COPD. 78 participants will take doxofylline or a placebo for 4 weeks, then switch. The main goal is to see if doxofylline increases the amount of air they can exhale in one second (FEV1).
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
doxofylline (Ansimar)
What this could lead to
If it works, this could offer a new add-on option to help COPD patients breathe better when inhalers alone aren't enough.
What could go wrong
This is a small, early-phase trial with only 78 people over 4 weeks. Results may not apply to all COPD patients, and doxofylline may cause side effects like nausea or headache.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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L. Sacco Hospital
Milan, 20157, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••