Brain chemical dopamine may unlock motivation in depressed patients
NCT ID NCT05909267
First seen Apr 06, 2026 · Last updated May 14, 2026 · Updated 5 times
Summary
This study looks at whether increasing dopamine can help with motivation and movement problems in people with major depression who have signs of inflammation. Researchers will give a dopamine-boosting drug or a placebo to 165 participants (depressed patients and healthy volunteers) and measure their effort, walking speed, and reward-seeking behavior. The goal is to understand the link between inflammation, dopamine, and depression symptoms, not to test a new treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Klinik für Psychiatrie und Psychotherapie
RECRUITINGSteglitz, 12203, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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