Can brain training help depressed young adults stop ruminating?
NCT ID NCT06219681
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether real-time fMRI neurofeedback could help young adults with major depression reduce repetitive negative thinking. Participants received either real or fake feedback while their brain activity was monitored. The trial was terminated early, so the findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- real-time fMRI neurofeedback
- What this could lead to
- If successful, this approach could point toward a non-drug therapy for reducing repetitive negative thinking in depression.
- What could go wrong
- The trial was terminated early, so results are limited. It was a small, early-stage study, and the intervention may not work for everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Laureate Institute for Brain Research
Tulsa, Oklahoma, 74136, United States
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