Can brain training help depressed young adults stop ruminating?
NCT ID NCT06219681
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether real-time fMRI neurofeedback could help young adults with major depression reduce repetitive negative thinking. Participants received either real or fake feedback while their brain activity was monitored. The trial was terminated early, so the findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
real-time fMRI neurofeedback
What this could lead to
If successful, this approach could point toward a non-drug therapy for reducing repetitive negative thinking in depression.
What could go wrong
The trial was terminated early, so results are limited. It was a small, early-stage study, and the intervention may not work for everyone.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Laureate Institute for Brain Research
Tulsa, Oklahoma, 74136, United States