Experimental virus injection takes aim at childhood brain tumors

NCT ID NCT07424092

Recruiting now Disease control Sponsor: Clinica Universidad de Navarra, Universidad de Navarra Source: ClinicalTrials.gov ↗

First seen Feb 21, 2026 · Last updated Jun 12, 2026 · Updated 13 times

Summary

This study tests a treatment called DNX-2401, a modified virus injected directly into brain tumors, for children and young adults with recurrent or hard-to-treat high-grade brain tumors. The goal is to see if this single injection can shrink tumors and help patients live longer. About 39 participants will receive the injection during surgery and be monitored for safety and tumor response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Cancer Center Clínica Universidad de Navarra
RECRUITING

Pamplona, Navarre, 31008, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Princess Máxima Centrum
NOT_YET_RECRUITING

Utrecht, 3584, Netherlands

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

EMBRYONAL TUMOR OF BRAIN EPENDYMOMA HIGH GRADE GLIOMA PEDIATRIC RECURRENCE REFRACTORY YOUNG ADULT