Powerful 4-Drug cocktail aims to crush myeloma early

NCT ID NCT03500445

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 25 times

Summary

This study tests a combination of four drugs (daratumumab, carfilzomib, lenalidomide, and dexamethasone) in 75 people newly diagnosed with multiple myeloma. The goal is to see how many achieve a very deep remission (stringent complete response) and have no detectable cancer cells after 8 cycles of treatment. This approach aims to control the disease aggressively from the start, but ongoing management is still needed.

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Contacts and locations

Locations

  • The University of Chicago

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.