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Can dignity therapy and mindfulness lift distress in serious illness?

NCT ID NCT06549075

Symptom relief Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 20, 2026 · Last updated Oct 21, 2026 · Updated 1 time

Summary

Researchers at a Swiss hospital are testing whether adding personalized therapeutic support to standard palliative care helps people with life-limiting illnesses feel more dignified and mentally well. Participants choose from three approaches: Dignity Therapy, CALM Therapy, or mindfulness training, delivered in two 60-minute sessions. The trial compares this extra support with standard palliative care alone and measures changes with questionnaires and interviews.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
personalized modular therapeutic support combining Dignity Therapy, CALM Therapy, and mindfulness training
What this could lead to
If it works, this could give palliative care teams a flexible, patient-chosen way to help people with serious illness feel more dignified and emotionally supported.
What could go wrong
The trial is small and early, so results may not hold in larger groups. Some patients may find the sessions tiring or emotionally demanding, and the benefit may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Sep 2024

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Informed Consent * Patients seen by the palliative consultation-liaison service at the University Hospital Basel as an in- or outpatient * Suffering from a life-limiting serious illness (≤ 18 months) * ≥ 18 years of age * Willingness and capacity to commit to three study visits Exclusion criteria: * Delirious (ICD-10: F05.9) * Inability to give consent (lack of decisional capacity to consent) * Inability to follow the procedures of the study due to psychological disorders, dementia, or other cognitively impairment of the participant, * Too ill to complete the requirements of the protocol * Unable to understand, speak and read German

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm glioblastoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Glioblastoma Life-limiting illness Prostate cancer

Contacts and locations

Locations

  • University Hospial Basel

    Basel, 4031, Switzerland

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