Carbs vs fats: which diet is better for your heart? oxford launches new study

NCT ID NCT05973539

First seen May 24, 2026 · Last updated Jun 22, 2026 · Updated 8 times

Summary

This study from the University of Oxford looks at how eating a diet very high in either carbohydrates or fats (65% of calories) changes blood fat levels and liver fat in 60 healthy adults. Participants will follow one of two diets for a short time, and researchers will measure changes in triglycerides and liver fat using blood tests and MRI. The goal is to understand which diet composition may lower the risk of heart disease and diabetes, and whether a person's genes play a role.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Oxford Centre for Diabetes, Endocrinology and Metabolism

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Diet: eucaloric diet enriched in either carbohydrates or fat (both contributing to 65% total energy intake)

What this could lead to

If successful, this study could help identify which diet composition is better for heart and metabolic health, and how genes influence that.

What could go wrong

This is a small, early-stage observational study (60 participants) that does not test a treatment. Results may not apply to everyone and won't directly change medical practice.

Conditions

The condition(s) this trial relates to.

Nutritional and Metabolic Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.