Can a mediterranean diet lower stress hormones?
NCT ID NCT07873762
First seen Oct 14, 2026 · Last updated Oct 15, 2026 · Updated 1 time
Summary
Researchers at Acibadem University are studying whether a personalized calorie-reduced Mediterranean-style diet changes perceived stress, morning cortisol and sleep quality in adults with overweight or obesity. Thirty adults aged 18 to 49 follow an individually planned diet for 12 weeks and attend weekly check-ins. The team measures weight and body composition weekly, and stress, cortisol and sleep at the start and end of the study. They also look at whether stress, cortisol, sleep and physical activity relate to how much weight and fat participants lose.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A personalized calorie-reduced Mediterranean-style diet with weekly check-ins
- What this could lead to
- If the diet changes stress, sleep or cortisol alongside weight, doctors could pay more attention to these factors when treating overweight and obesity.
- What could go wrong
- This is a small single-arm study of 30 adults, so it cannot prove the diet causes any change. Stress, sleep and cortisol shift for many reasons, and results may not apply to other groups.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Jul 2020
- Finished
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Oct 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 49 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-49 years * Body mass index (BMI) ≥25 kg/m² * Seeking weight loss and willing to participate in the study Exclusion Criteria: * Pregnancy * Menopause * Any diagnosed metabolic disease * Use of psychiatric medication * Regular alcohol consumption (\>2 drinks/day or \>9 drinks/week) * Current smoking * Habitual vigorous physical activity
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Samsun FBM tıp merkezi
Samsun, Turkey (Türkiye)
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