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Hot or cold? scientists probe whether meal temperature flips the body's fullness switch

NCT ID NCT05822167

Knowledge-focused Sponsor: Khyber Medical University Peshawar Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Oct 15, 2026 · Last updated Oct 16, 2026 · Updated 1 time

Summary

Researchers at Khyber Medical University Peshawar are studying whether the temperature of a high-protein meal affects feelings of fullness, appetite hormones, chewing time and brain activity. Thirteen healthy adults with a body mass index between 18.5 and 24.9 eat the same 500-calorie meal served cold, warm or hot. The team measures satiety scores, gut hormones such as GLP-1 and CCK, chewing counts, and EEG brain waves before and after eating.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-protein meals served at cold, warm or hot temperatures
What this could lead to
If meal temperature changes fullness signals, it could inform simple dining habits that help people feel satisfied with less food.
What could go wrong
The study is very small, with 13 healthy young adults, so any patterns may not hold for other people or translate into lasting weight control.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

13 people

The number who actually took part.

Started

Apr 2023

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy individuals of age 25- 35 years * BMI ranged between 18.5 and 24.9 Exclusion Criteria: * Chronic diseases, diabetes, endocrine disorder, * Any bariatric surgery that interfered with gastrointestinal functions, * Smoking, * Dieting, * Pregnancy, lactation, * Taking medication or supplements. * Psychiatry illnesses or dental problems will be excluded. * Females with the history of premenstrual syndrome will be excluded. * Gastrointestinal Complications * Following Special diets * Food allergy to food used in the trial

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Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity & overweight

Contacts and locations

Locations

  • Khyber Medical University

    Peshawar, KPK, 25000, Pakistan

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