Diet plan may help fight muscle weakness in liver cirrhosis

NCT ID NCT07625085

First seen Jun 10, 2026 · Last updated Jun 22, 2026 · Updated 4 times

Summary

Liver cirrhosis often causes muscle weakness and frailty, even in stable patients. This study tested whether a personalized diet with extra calories and protein, along with nutrition counseling, could improve muscle strength and quality of life. About 70 adults with stable cirrhosis were randomly assigned to either the diet plan or usual care, and followed for 16 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Policlinico Umberto I

    Rome, Lazio, 00185, Italy

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

individualized diet plan (calorie and protein targets from regular foods, plus nutrition counseling)

What this could lead to

If it works, this could show that simple dietary changes can help people with liver cirrhosis maintain muscle strength and reduce frailty, improving daily life.

What could go wrong

This is a small, completed study with only 70 participants, so results may not apply to everyone. Diet plans can be hard to follow, and the effect on muscle strength may be modest.

Conditions

The condition(s) this trial relates to.

cirrhosis of liver

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.