Heart patients may ditch blood thinners after ablation, major trial investigates

NCT ID NCT06871228

Recruiting now Disease control Sponsor: Beijing Anzhen Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people with atrial fibrillation (AF) can safely stop taking blood thinners after a successful heart ablation procedure. About 4,100 adults aged 18-80 who have been on blood thinners for at least 2 months after ablation and have no signs of AF recurrence will be randomly assigned to either stop or continue their medication. All participants will use smartwatches and regular heart monitors to catch any return of AF. The goal is to see if stopping blood thinners reduces bleeding risks without increasing the chance of stroke or death.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation Hemorrhage Thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF)

Contacts and locations

Locations

Beijing Anzhen Hospital
RECRUITING

Beijing, Beijing Municipality, 100029, China
Chengdu Fifth People's Hospital
NOT_YET_RECRUITING

Chengdu, Sichuan, 611130, China
First Affiliated Hospital of Dalian Medical University
NOT_YET_RECRUITING

Dalian, Liaoning, 116023, China
Guangdong Provincial People's Hospital
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510080, China
Henan Provincial Chest Hospital
NOT_YET_RECRUITING

Zhengzhou, Henan, 450003, China
Liaocheng Heart Hospital
NOT_YET_RECRUITING

Liaocheng, Shandong, 252299, China
Liaocheng People's Hospital
NOT_YET_RECRUITING

Liaocheng, Shandong, 252000, China
Luohe Central Hospital
NOT_YET_RECRUITING

Luohe, Henan, 462003, China
Ningbo No.2 Hospital
NOT_YET_RECRUITING

Ningbo, Zhejiang, 315000, China
Qilu Hospital of Shandong University
NOT_YET_RECRUITING

Jinan, Shandong, 250012, China
Shengjing Hospital Affiliated to China Medical University
NOT_YET_RECRUITING

Shenyang, Liaoning, 110004, China
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
NOT_YET_RECRUITING

Hangzhou, Zhejiang, 310009, China
The Affiliated Hospital of Xuzhou Medical University
NOT_YET_RECRUITING

Xuzhou, Jiangsu, 221002, China
The First Affiliated Hospital of Anhui Medical University
NOT_YET_RECRUITING

Hefei, Anhui, 230022, China
The First Affiliated Hospital of Harbin Medical University
NOT_YET_RECRUITING

Harbin, Heilongjiang, 150001, China
The First Affiliated Hospital of Nanjing Medical University
NOT_YET_RECRUITING

Nanjing, Jiangsu, 210036, China
The First Affiliated Hospital of Zhejiang University School of Medicine
NOT_YET_RECRUITING

Hangzhou, Zhejiang, 310000, China
The First Hospital of Jilin University
NOT_YET_RECRUITING

Changchun, Jilin, 130021, China
The Second Affiliated Hospital of Harbin Medical University
NOT_YET_RECRUITING

Harbin, Heilongjiang, 150085, China
The Second Hospital of Hebei Medical University
NOT_YET_RECRUITING

Shijiazhuang, Hebei, 050000, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
NOT_YET_RECRUITING

Wuhan, Hubei, 430030, China
Wuhan Asia Heart Hospital
NOT_YET_RECRUITING

Wuhan, Hubei, 430022, China

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