Can triple therapy kickstart diabetes remission? new study aims to find out

NCT ID NCT07374328

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two triple-drug combinations to see which works better for controlling blood sugar and possibly achieving diabetes remission in people newly diagnosed with type 2 diabetes. About 240 adults aged 18-65 with very high blood sugar (HbA1c ≥9%) will be randomly assigned to receive either an injectable drug (semaglutide) plus two oral medications, or three oral medications. After 6 months of treatment, those whose blood sugar drops below a certain level will stop all diabetes drugs and be monitored for 3 months to see if remission is maintained.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital, Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, 510260, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••