Could a common steroid make kids' pain relief last longer after hand surgery?
NCT ID NCT05887778
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looked at whether giving dexamethasone before a nerve block can prolong pain relief after hand or wrist surgery in children. Ninety children were randomly assigned to receive a small dose, a large dose, or a placebo. The main goal was to see how long it took before they needed additional pain medication.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Dexamethasone
- What this could lead to
- If it works, this could provide longer-lasting pain relief after pediatric hand/wrist surgery, reducing the need for strong painkillers like opioids.
- What could go wrong
- This is a small, completed Phase 4 trial with only 90 children. Results may not apply to all surgeries or ages, and dexamethasone can raise blood sugar or affect immunity.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
90 people
The number who actually took part.
- Started
-
Sep 2023
- Finished
-
Apr 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
3 months to 18 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * children scheduled for hand/wrist surgery * body weight \> 5kg Exclusion Criteria: * infection at the site of the regional blockade * coagulation disorders * immunodeficiency * ASA= or \>4 * steroid medication in regular use
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Poznan University of Medical Sciences
Poznan, Poland
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Other studies related to the condition(s) this trial covers.
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