Promising combo targets hard-to-treat breast cancer

NCT ID NCT04556773

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called trastuzumab deruxtecan (T-DXd) combined with other anti-cancer medicines in people with metastatic HER2-low breast cancer. The goal is to find safe doses and see if the combination can shrink tumors or slow the cancer's growth. About 138 adults with this type of breast cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Leuven, 3000, Belgium

  • Research Site

    Ottignies, 1340, Belgium

  • Research Site

    Goiânia, 74605-070, Brazil

  • Research Site

    Porto Alegre, 90035-003, Brazil

  • Research Site

    Porto Alegre, 90110-270, Brazil

  • Research Site

    São Paulo, 03102-002, Brazil

  • Research Site

    São Paulo, 04543-000, Brazil

  • Research Site

    Kelowna, British Columbia, V1Y 5L3, Canada

  • Research Site

    Québec, Quebec, G1J 1Z4, Canada

  • Research Site

    Villejuif, 94805, France

  • Research Site

    Monterrey, 64710, Mexico

  • Research Site

    Moscow, 115478, Russia

  • Research Site

    Moscow, 143442, Russia

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    Saint Petersburg, 199226, Russia

  • Research Site

    Seoul, 03080, South Korea

  • Research Site

    Seoul, 03722, South Korea

  • Research Site

    Seoul, 05505, South Korea

  • Research Site

    Seoul, 06351, South Korea

  • Research Site

    Kaohsiung City, 82445, Taiwan

  • Research Site

    Taichung, 40443, Taiwan

  • Research Site

    Taipei, 100, Taiwan

  • Research Site

    Taipei, 11217, Taiwan

  • Research Site

    Taipei, 114, Taiwan

  • Research Site

    Taipei, 235, Taiwan

  • Research Site

    Taoyuan, 333, Taiwan

  • Research Site

    Commack, New York, 11725, United States

  • Research Site

    Harrison, New York, 10604, United States

  • Research Site

    New York, New York, 10029, United States

  • Research Site

    New York, New York, 10065, United States

  • Research Site

    Uniondale, New York, 11553, United States

  • Research Site

    Chapel Hill, North Carolina, 27514, United States

  • Research Site

    Chattanooga, Tennessee, 37404, United States

  • Research Site

    Germantown, Tennessee, 38138, United States

  • Research Site

    Fort Worth, Texas, 76104, United States

  • Research Site

    East Melbourne, 3002, Australia

  • Research Site

    Westmead, 2145, Australia

  • Research Site

    Edegem, 2650, Belgium