Can matching depression therapy to your weaknesses or strengths boost results?

NCT ID NCT04576182

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing two types of talk therapy for major depression: supportive-expressive therapy and emotion-focused therapy. The goal is to see if people do better when the therapy matches their personal style—whether they tend to think deeply about their problems (insight) or process emotions strongly. 124 adults with depression will receive 16 weeks of therapy and be followed for 2 years. Researchers will track changes in depression symptoms using standard questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Supportive-expressive therapy and emotion-focused therapy (both behavioral interventions)

What this could lead to

If successful, this could help doctors choose the best talk therapy for each person with depression, making treatment more effective.

What could go wrong

This is a relatively small, early-stage study focused on understanding how therapies work, not on proving a new cure. Results may not apply to everyone with depression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Haifa

    RECRUITING

    Haifa, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••