Depression and heart disease: scientists investigate the role of 'Good' cholesterol

NCT ID NCT05099341

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at whether the quality and function of HDL (often called 'good' cholesterol) is different in people with depression compared to healthy controls. Researchers will analyze blood samples from 90 adults with moderate to severe depression and a control group. The goal is to better understand the link between depression and increased risk of heart disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could reveal why people with depression have higher heart disease risk, pointing toward new prevention strategies.

What could go wrong

This is an observational study, not a treatment trial. It may not find clear differences in HDL function, and any findings will need further validation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chu Dijon Bourgogne

    RECRUITING

    Dijon, 21000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••