Could depression change how Kids' asthma responds to treatment?

NCT ID NCT04617015

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 39 children with asthma to see if those with depression have a different type of airway response. Researchers tested whether an anticholinergic inhaler (ipratropium) works better in depressed versus non-depressed children. The goal was to better understand this possible asthma subtype, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ipratropium Bromide (an anticholinergic inhaler)

What this could lead to

If successful, this could point toward a personalized treatment approach for children with asthma and depression, using a different type of inhaler.

What could go wrong

This is a very small, early-phase study with only 39 participants. It is designed to gather information, not to prove a treatment works. Results may not apply to all children with asthma and depression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma childhood onset asthma Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Women and Children's Hospital of Buffalo

    Buffalo, New York, 14222, United States