Ice or spray? study tests simple ways to take the sting out of dental needles
NCT ID NCT07703553
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study tests whether cooling the injection site with an ice pen, applying a numbing spray, or using both together can reduce pain from dental anesthesia needles. About 192 adults needing a standard dental injection will be randomly assigned to one of four groups: ice alone, spray alone, both, or no pre-treatment. Participants will rate their pain right after the needle goes in, and researchers will also observe their reactions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 10% lidocaine spray and ice pen (cryotherapy)
- What this could lead to
- If successful, this could identify a simple, low-cost method to make dental injections less painful for patients.
- What could go wrong
- This is a small, single-center trial, so results may not apply to all dental settings. Pain is subjective, and individual responses vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Harran University Faculty of Dentristry,Departman of Endodonti
Sanliurfa, Outside of the US, 63300, Turkey (Türkiye)
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