Ice or spray? study tests simple ways to take the sting out of dental needles

NCT ID NCT07703553

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether cooling the injection site with an ice pen, applying a numbing spray, or using both together can reduce pain from dental anesthesia needles. About 192 adults needing a standard dental injection will be randomly assigned to one of four groups: ice alone, spray alone, both, or no pre-treatment. Participants will rate their pain right after the needle goes in, and researchers will also observe their reactions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
10% lidocaine spray and ice pen (cryotherapy)
What this could lead to
If successful, this could identify a simple, low-cost method to make dental injections less painful for patients.
What could go wrong
This is a small, single-center trial, so results may not apply to all dental settings. Pain is subjective, and individual responses vary.

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Harran University Faculty of Dentristry,Departman of Endodonti

    Sanliurfa, Outside of the US, 63300, Turkey (Türkiye)

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