Dental implant showdown: which connection design saves more bone?
NCT ID NCT03528330
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This study compares two types of dental implant connections — internal hexagon and conical — to see which one leads to better bone preservation, fewer complications, and healthier gums. Twenty adults needing two implant-supported crowns will receive one of each connection type, allowing a direct head-to-head comparison. Researchers will measure bone levels, implant stability, and any failures or prosthetic issues over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dental implant with internal hexagon connection or conical connection
- What this could lead to
- If one connection type clearly outperforms the other, dentists may adopt it to improve implant longevity and reduce bone loss.
- What could go wrong
- This is a small, early-stage study with only 20 participants, so results may not apply to all patients. Differences between connections may be minor or not clinically meaningful.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
20 people
The number who actually took part.
- Started
-
Jan 2018
- Finished
-
Dec 2019
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
25 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * able to sign an informed consent form * aged 25 years or more * Any patient requiring two implant-supported crowns in the lower or upper jaw * Kennedy class I, II, and III; * teeth extracted at least 6 months before implant placement; * sufficient bone volumes to accommodate dental implants without augmentation procedure Exclusion Criteria: * General medical and/or psychiatric contraindications to implant surgery, * Pregnancy or nursing, * Heavy smoking (more than 10 cigarettes/day), * Treatment with anticoagulant drugs (International Normalized Ratio under 1.8), bisphosphonates, steroid therapy or anticonvulsants drugs. * No regenerated bone * Untreated Periodontal disease and inability of the patient to maintain reasonable oral hygiene according to study requirements. * Patients with history of alcohol, narcotics or drug abuse. (Alcoholism: more than two bottles of beer per day) * Patients receiving radiotherapy, chemotherapy or any other immunosuppressive treatment, or who have been administered radiotherapy in the last 5 years. (Patients through at any time received radiotherapy to the head and neck region should be excluded anyway.) * Metabolic bone disorders * Uncontrolled bleeding disorders such as: hemophilia, thrombocytopenia, granulocytopenia. * Degenerative diseases. * Osteoradionecrosis. * Renal failure. * Organ transplant recipients. * HIV positive. * Malignant diseases. * Diseases that compromise the immune system. * Unbalanced diabetes mellitus. (HbA1c above 6.5), Uncontrolled endocrine diseases * Psychotic diseases. * Hypersensitivity to one of the components of the implant in general and titanium in particular. * Women who are pregnant or lactating. * Lack of patient cooperation. * Parafunctional habits, such as Bruxism or Temporomandibular joint disease. * Various pathologies of the oral mucosa for example: Benign mucous pemphigoid, desquamative ginigivitis, erosive lichen planus, malignancy of oral cavity, bolus erosive diseases of the oral mucosa.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Bone loss, alveolar are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Clínica Odontológica de la Universitat de Valencia, Fundación Lluis Alcanyis
Valencia, 46010, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A squirt of gel inside a dental implant could stop it from failing
- 3D-Printed short implants could offer new option for jawbone loss
- Short implants, long promise: 5-Year study tests durability in tough jaw spots
- Vitamin d deficiency may undermine dental implants — trial tests if supplements can fix it
- New study tests better ways to build jawbone for dental implants
- Gum graft boost: platelet gel or probiotics for better implants?