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Gum graft boost: platelet gel or probiotics for better implants?

NCT ID NCT07596758

Disease control Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding platelet-rich fibrin or probiotics to immediate dental implant surgery with gum grafting improves healing and implant success. About 22 adults needing a single front tooth implant will be enrolled. Researchers will measure gum health and bone changes around the implant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 22 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 20 to 45 years. * Systemically healthy patients eligible for implant surgery. * Patients requiring extraction of a single non-restorable tooth indicated for immediate implant placement. * Implant sites located in the maxillary esthetic or para-esthetic zone. * Sites with sufficient apical and/or palatal bone to permit correct three-dimensional implant positioning and achieve adequate primary stability. * Sites suitable for simultaneous subepithelial connective tissue grafting. * Patients with acceptable oral hygiene and good compliance with periodontal and implant treatment. * Patients willing to attend all follow-up visits and comply with study instructions. Exclusion Criteria: * Medically compromised patients or patients with systemic conditions that may contraindicate implant surgery or interfere with healing. * Smokers. * Pregnant or lactating women. * Patients with uncontrolled periodontal disease or poor oral hygiene. * Patients with acute infection at the intended implant site. * Patients with insufficient bone volume preventing immediate implant placement with adequate primary stability. * Patients with a history of head and neck radiotherapy or chemotherapy. * Patients receiving bisphosphonates or other medications known to affect bone metabolism or soft tissue healing. * Patients with parafunctional habits that may jeopardize implant stability or restorative success. * Patients unwilling or unable to complete the follow-up period.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental implant failed

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • faculty of dentistry, kafrelsheikh University

    Kafr ash Shaykh, Kafrelsheikh, 214312, Egypt

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