New surgery for rectal cancer could cut leak risk and stoma need
NCT ID NCT01876901
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 2 trial tested a two-step surgical procedure called delayed coloanal anastomosis (2SCA) in 124 patients with medium or lower rectal cancer. The goal was to see if this technique lowers the rate of dangerous leaks at the surgical connection and reduces the need for a colostomy bag. Results showed that the procedure may be safer than the standard immediate anastomosis, with fewer leaks and fewer patients needing a stoma.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
2-stage pull-through colo-anal anastomosis without prophylactic derivation (2SCA) - a surgical procedure
What this could lead to
If successful, this surgical technique could lower the risk of post-surgery leaks and reduce the need for temporary or permanent stomas in rectal cancer patients.
What could go wrong
This is a phase 2 trial with a relatively small sample size (124 patients). The results may not apply to all patients, and the procedure still carries surgical risks like infection or bleeding.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU DE BORDEAUX - Hôpital Saint André
Bordeaux, Aquitaine, 33000, France
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CHU de GRENOBLE
Grenoble, Auvergne-Rhône-Alpes, 38000, France
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Centre Alexis Vautrin
Vandœuvre-lès-Nancy, Lorraine, 54000, France
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Centre Léon Bérard
Lyon, Auvergne-Rhône-Alpes, 69000, France
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Chu de Nancy
Nancy, Lorraine, 54000, France
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Clinique Du Tonkin
Villeurbanne, Auvergne-Rhône-Alpes, 69000, France
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HOSPICES CIVILS DE LYON - Hôpital de la Croix Rousse
Lyon, Auvergne-Rhône-Alpes, 69000, France
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Institut Bergonié
Bordeaux, Aquitaine, 33000, France
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Institut Paoli Calmettes
Marseille, Bouche Du Rhône, 13000, France