Heart showdown: stents vs. bypass surgery in diabetes patients
NCT ID NCT05831085
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two advanced heart procedures—stenting guided by imaging and blood flow tests (PCI) versus bypass surgery (CABG)—in 1,500 people with diabetes and three blocked coronary arteries. The goal is to see which approach better prevents major events like death, heart attack, or stroke. Participants are randomly assigned to one procedure, and both groups also receive modern medications for heart health and diabetes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Percutaneous coronary intervention (stenting) with imaging and physiology guidance, and coronary artery bypass grafting (bypass surgery)
What this could lead to
If this trial succeeds, it could show that modern stenting guided by advanced imaging is as good as or better than bypass surgery for people with diabetes and multiple blocked arteries, potentially offering a less invasive option.
What could go wrong
This is a large trial, but results may not apply to everyone with diabetes or heart disease. Both procedures carry risks like bleeding, infection, or heart attack, and the study is still recruiting, so outcomes are not yet known.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Asan Medical Center
RECRUITINGSeoul, South Korea
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Bucheon Sejong Hospital
RECRUITINGBucheon-si, South Korea
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Chonnam National University Hospital
RECRUITINGGwangju, South Korea
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Chungnam National University Hospital
RECRUITINGDaejeon, South Korea
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Daegu Catholic University Medical Center
NOT_YET_RECRUITINGDaegu, South Korea
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Dong-A Medical Center
RECRUITINGPusan, South Korea
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Fortis Escorts Heart Institute
RECRUITINGNew Delhi, India
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Fuwai Hospital, Chinese Academy of Medical Sciences (CAMS)
RECRUITINGBeijing, China
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Gachon University Gil Hospital
NOT_YET_RECRUITINGIncheon, South Korea
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Gangneung Asan Hospital
NOT_YET_RECRUITINGGangneung, South Korea
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Hanyang University Seoul Hospital
NOT_YET_RECRUITINGSeoul, South Korea
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Keimyung University Dongsan Medical Center
RECRUITINGDaegu, South Korea
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Konyang University Hospital
WITHDRAWNDaejeon, South Korea
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Medanta - The Medicity
RECRUITINGGurugram, India
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Mody Harvard Cardiac Institute
RECRUITINGBathinda, India
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National Health Insurance Service Ilsan Hospital
RECRUITINGIlsan, South Korea
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National Heart Centre Singapore (NHCS)
RECRUITINGSingapore, Singapore
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National Taiwan University Hospital
RECRUITINGTaipei, Taiwan
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Palo Alto VA Medical Center
RECRUITINGPalo Alto, California, 94304, United States
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Pauls Stradins Clinical University Hospital
RECRUITINGRiga, Latvia
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Pusan National University Yangsan Hospital
RECRUITINGYangsan, South Korea
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Queen Mary Hospital
RECRUITINGHong Kong, Hong Kong
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SNU Boramae Medical Center
NOT_YET_RECRUITINGSeoul, South Korea
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Samsung Medical Center
RECRUITINGSeoul, South Korea
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Sarawak Heart Centre
RECRUITINGKota Samarahan, Malaysia
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Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHanzhou, China
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Seoul university Bundang hospital
RECRUITINGSeongnam-si, South Korea
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Siriraj Hospital
RECRUITINGBangkok, Thailand
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Siriraj Hospital
RECRUITINGBangkok, Thailand
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Srinagarind Hospital
RECRUITINGKhon Kaen, Thailand
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The Catholic Univ. of Korea Seoul St. Mary's hospital
RECRUITINGSeoul, South Korea
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The Catholic University of Korea, St. Vincent's Hospital
NOT_YET_RECRUITINGSuwon, South Korea
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The Catholic University of Korea, Uijeongbu ST. Mary's Hospital
RECRUITINGUijeongbu-si, South Korea
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Tsuchiura Kyodo Hospital
RECRUITINGTsuchiura, Japan
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Ulsan University Hospital
RECRUITINGUlsan, South Korea
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University Clinical Center of Serbia
RECRUITINGBelgrade, Serbia
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Victorian Heart Institute
RECRUITINGClayton, Australia
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Vilnius University Hospital Santaros Klinikos
RECRUITINGVilnius, Lithuania
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Yeungnam University Medical Center
NOT_YET_RECRUITINGDaegu, South Korea
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