Targeted drug trial aims to block growth signal in tough cancers
NCT ID NCT04439331
Summary
This study is testing a drug called defactinib in people with advanced cancers that have stopped responding to other treatments and have a specific genetic change called an NF2 mutation. The drug aims to block a protein that these cancer cells may need to grow. Researchers want to see if defactinib can shrink these tumors or stop them from getting worse.
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Contacts and locations
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Locations
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ECOG-ACRIN Cancer Research Group
Philadelphia, Pennsylvania, 19103, United States
Conditions
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