Experimental vaccine combo shows promise in brain cancer fight

NCT ID NCT03688178

First seen May 24, 2026 · Last updated Jun 10, 2026 · Updated 7 times

Summary

This study tests whether adding a special vaccine (dendritic cell vaccine) and an immune-boosting drug (varlilumab) to standard chemotherapy and radiation can help people with newly diagnosed glioblastoma live longer. About 43 participants will receive the vaccine and be randomly assigned to different pre-conditioning methods. The goal is to see if this approach can improve overall survival by better activating the immune system against the tumor.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

Conditions

Explore the condition pages connected to this study.