Tiny radioactive seeds tested again for stubborn skin cancers
NCT ID NCT04540588
First seen Jan 10, 2026 · Last updated Jun 23, 2026 · Updated 29 times
Summary
This study tested whether a second treatment with DaRT, a device that places tiny radioactive seeds directly into tumors, is safe and effective for people whose skin, mouth, or soft tissue cancers returned after initial DaRT therapy. Only 2 participants were enrolled, and researchers measured tumor shrinkage and side effects. The approach aims to control local disease without surgery.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Sharett institute, Hadassah University Hospital - Ein-Kerem
Jerusalem, 91120, Israel
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Diffusing Alpha Radiation Emitters Therapy (DaRT) device
What this could lead to
If it works, this could offer a retreatment option for patients whose skin, mouth, or soft tissue cancers come back after initial DaRT therapy.
What could go wrong
This is a very early study with only 2 participants, so results are not generalizable. The treatment involves inserting radioactive seeds into tumors, which carries risks like local side effects or incomplete tumor coverage.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.