Radioactive seeds zapped tumors from inside – early trial shows promise

NCT ID NCT03737734

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device called DaRT that delivers alpha radiation directly into tumors. It is for people with skin cancer, mouth tumors, or superficial soft tissue sarcoma who have not responded to other treatments or cannot have standard therapy. The goal is to see if the device can shrink tumors and how safe it is. Thirty participants are enrolled, and the study is active but no longer recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Diffusing Alpha Radiation Emitters Therapy (DaRT) device

What this could lead to

If it works, this could offer a new treatment option for people with certain skin, mouth, or soft tissue cancers who cannot have or refuse standard treatments.

What could go wrong

This is an early study with only 30 people, so results may not apply to everyone. The treatment involves inserting radioactive seeds into the tumor, which carries risks like infection or radiation side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

basal cell carcinoma Kaposi's sarcoma lip cancer oral cavity neoplasm skin cancer skin neoplasm soft tissue neoplasm Soft Tissue Neoplasms soft tissue sarcoma squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck tongue cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Davidof Cancer Institution at the Rabin Medical Center Israel

    Petah Tikva, 49100, Israel