New drug combo targets Hard-to-Treat thyroid cancer

NCT ID NCT01947023

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tested a combination of two targeted drugs, dabrafenib and lapatinib, in 23 people with advanced thyroid cancer that had a specific BRAF mutation and could not be removed by surgery. The main goal was to find the safest dose of lapatinib when given with dabrafenib, and to see how the drugs affect cancer-related proteins. The study is now complete but not yet published.

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Conditions

The condition(s) this trial relates to.

thyroid cancer thyroid gland carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States