Immunotherapy cocktail takes on deadly thyroid cancer

NCT ID NCT03181100

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether adding the immunotherapy drug atezolizumab to standard chemotherapy can help people with anaplastic or poorly differentiated thyroid cancer live longer. About 50 patients with advanced or inoperable cancer are receiving different drug combinations. The study is active but no longer recruiting new participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Atezolizumab (immunotherapy) plus chemotherapy drugs (bevacizumab, vemurafenib, cobimetinib, nab-paclitaxel, paclitaxel)

What this could lead to

If successful, this could offer a new treatment option for aggressive thyroid cancers that are hard to treat.

What could go wrong

This is a small, early-phase trial (50 people) with no results yet. The combination may not work better than standard treatments and could have serious side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

poorly differentiated thyroid gland carcinoma thyroid cancer thyroid gland carcinoma thyroid gland undifferentiated (anaplastic) carcinoma Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States