Can brain tumor patients safely reduce their medication? new study investigates
NCT ID NCT07110246
First seen Nov 10, 2025 · Last updated May 13, 2026 · Updated 29 times
Summary
This study looks at whether people with a slow-growing brain tumor (low-grade glioma) that has a specific gene change (BRAF V600) can safely stop or lower their dose of two targeted drugs (dabrafenib and trametinib) after taking them for 12-24 months. About 96 participants will either stop the drugs completely or slowly reduce the dose over 6 months. The goal is to see if the tumor stays under control with less medication.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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John Hopkins Medical Center
RECRUITINGBaltimore, Maryland, 21287, United States
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Louis Children's Hospital Washington University in St. Louis
RECRUITINGSt Louis, Missouri, 63110, United States
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
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Contact
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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