Scientists investigate why cystinosis causes early aging

NCT ID NCT07319091

Recruiting now Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This study looks at how energy production inside cells (mitochondria) works in people with cystinosis, a rare disease that causes cystine buildup and early aging. Researchers will measure cell energy activity in 25 patients and compare it to healthy people. The goal is to understand why cystinosis leads to bone disease and other complications, which could help find new treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could uncover the biological causes of premature aging and bone disease in cystinosis, pointing toward new treatment targets.
What could go wrong: This is a small, early observational study (25 participants) that measures cellular activity, not a treatment trial. It may not lead directly to therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cystinosis muscle tissue disorder nephropathic cystinosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYSTINOSIS NATIVE KIDNEY

Contacts and locations

Locations

Service de Néphologie et endocrinologie pédiatrique, Hôpital Arnaud de Villeneuve
RECRUITING

Montpellier, 34295, France
Service de Néphrologie pédiatrique, Hôpital Jeanne de Flandre
RECRUITING

Lille, 59000, France
Service de Néphrologie pédiatrique, Hôpital Necker-Enfants Malades
RECRUITING

Paris, 75015, France
Service de Néphrologie pédiatrique, Hôpital Robert Debré
RECRUITING

Paris, 75019, France
Service de Néphrologie pédiatrique, Hôpital de la Timone
RECRUITING

Marseille, 13385, France
Service de Néphrologie-Dialyse-Transplantation pédiatrique, Hôpital d'enfants Brabois
RECRUITING

Vandœuvre-lès-Nancy, 54511, France
Service de Néphrologie-transplantation rénale adultes, Hôpital Necker-Enfants Malades
RECRUITING

Paris, 75015, France
Service de néphrologie et exploration fonctionnelle rénale, Hôpital Edouard Herriot, Hospices Civils de Lyon
RECRUITING

Lyon, 69003, France
Service de néphrologie pédiatrique, Hôpital Femme Mère Enfant, Hospices Civils de Lyon
RECRUITING

Bron, 69677 Bron Cedex, France

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