New pill for cystic fibrosis lung disease tested in small trial
NCT ID NCT05865886
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new medicine called BI 1291583 in 22 adults with cystic fibrosis bronchiectasis, a lung condition that causes coughing and infections. Participants took one tablet daily for 12 weeks, and the study checked if the medicine was safe and well-tolerated. The trial was completed and aimed to gather early safety data.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AOU San Luigi Gonzaga
Orbassano (TO), 10043, Italy
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Amsterdam UMC, location VUMC
Amsterdam, 1081 HV, Netherlands
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Azienda Ospedaliera Meyer
Florence, 50139, Italy
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Azienda Ospedaliera Universitaria Integrata Verona
Verona, 37126, Italy
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Brussels - UNIV UZ Brussel
Brussels, 1090, Belgium
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Central Florida Pulmonary Group
Altamonte Springs, Florida, 32701, United States
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Charité - Universitätsmedizin Berlin
Berlin, 13353, Germany
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Chest Medicine Associates
South Portland, Maine, 04106, United States
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Columbia University Medical Center-New York Presbyterian Hospital
New York, New York, 10032, United States
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HOP Arnaud de Villeneuve
Montpellier, 34295, France
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario Ramon Y Cajal
Madrid, 28049, Spain
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Hôpital Charles Nicolle
Rouen, 76031, France
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Hôpital Cochin
Paris, 75679, France
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IRCCS Fondazione Ospedale Maggiore
Milan, 20122, Italy
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Istituto G. Gaslini
Genova, 16147, Italy
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Klinikum der Universität München AÖR
München, 80336, Germany
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Medizinische Hochschule Hannover
Hanover, 30625, Germany
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National Jewish Health
Denver, Colorado, 80206, United States
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Northwell Health Physician Partners
New York, New York, 10028, United States
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Oregon Health and Sciences University
Portland, Oregon, 97239, United States
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Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH
Essen, 45239, Germany
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Universitair Medisch Centrum Utrecht
Utrecht, 3584 CX, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A smartphone tool may help cystic fibrosis patients survive the lung transplant waitlist
- Gum treatment may lower lung flare-ups in bronchiectasis patients
- Can a smartphone app reveal how CF treatments really work at home?
- Can a daily pill cut dangerous lung Flare-Ups in bronchiectasis?
- Can a peer coach help young people take control of their chronic illness?
- Could a single antibiotic be enough for cystic fibrosis lung infections?