New pill for cystic fibrosis lung disease tested in small trial

NCT ID NCT05865886

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new medicine called BI 1291583 in 22 adults with cystic fibrosis bronchiectasis, a lung condition that causes coughing and infections. Participants took one tablet daily for 12 weeks, and the study checked if the medicine was safe and well-tolerated. The trial was completed and aimed to gather early safety data.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AOU San Luigi Gonzaga

    Orbassano (TO), 10043, Italy

  • Amsterdam UMC, location VUMC

    Amsterdam, 1081 HV, Netherlands

  • Azienda Ospedaliera Meyer

    Florence, 50139, Italy

  • Azienda Ospedaliera Universitaria Integrata Verona

    Verona, 37126, Italy

  • Brussels - UNIV UZ Brussel

    Brussels, 1090, Belgium

  • Central Florida Pulmonary Group

    Altamonte Springs, Florida, 32701, United States

  • Charité - Universitätsmedizin Berlin

    Berlin, 13353, Germany

  • Chest Medicine Associates

    South Portland, Maine, 04106, United States

  • Columbia University Medical Center-New York Presbyterian Hospital

    New York, New York, 10032, United States

  • HOP Arnaud de Villeneuve

    Montpellier, 34295, France

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Ramon Y Cajal

    Madrid, 28049, Spain

  • Hôpital Charles Nicolle

    Rouen, 76031, France

  • Hôpital Cochin

    Paris, 75679, France

  • IRCCS Fondazione Ospedale Maggiore

    Milan, 20122, Italy

  • Istituto G. Gaslini

    Genova, 16147, Italy

  • Klinikum der Universität München AÖR

    München, 80336, Germany

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • Northwell Health Physician Partners

    New York, New York, 10028, United States

  • Oregon Health and Sciences University

    Portland, Oregon, 97239, United States

  • Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH

    Essen, 45239, Germany

  • Universitair Medisch Centrum Utrecht

    Utrecht, 3584 CX, Netherlands

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