New pill for cystic fibrosis lung disease tested in small trial

NCT ID NCT05865886

First seen Nov 18, 2025 · Last updated Jun 16, 2026 · Updated 35 times

Summary

This study tested a new medicine called BI 1291583 in 22 adults with cystic fibrosis bronchiectasis, a lung condition that causes coughing and infections. Participants took one tablet daily for 12 weeks, and the study checked if the medicine was safe and well-tolerated. The trial was completed and aimed to gather early safety data.

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Contacts and locations

Locations

  • Amsterdam UMC, location VUMC

    Amsterdam, 1081 HV, Netherlands

  • Azienda Ospedaliera Meyer

    Florence, 50139, Italy

  • Azienda Ospedaliera Universitaria Integrata Verona

    Verona, 37126, Italy

  • Charite Universitätsmedizin Berlin KöR

    Berlin, 13353, Germany

  • Hospital Universitari Vall D Hebron

    Barcelona, 08035, Spain

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • Northwell Health Physician Partners

    New York, New York, 10028, United States

  • Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH

    Essen, 45239, Germany

  • UZ Leuven

    Leuven, 3000, Belgium

  • Universitair Medisch Centrum Utrecht

    Utrecht, 3584 CX, Netherlands

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • Universitätsklinikum Jena

    Jena, 07747, Germany

Conditions

Explore the condition pages connected to this study.