Magic Mushroom-Like drug could ease depression and anxiety in one dose

NCT ID NCT06820723

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 27 times

Summary

This study tests whether a single oral dose of CYB003, a drug related to psilocybin, can help ease symptoms of depression and anxiety in 40 adults with major depressive disorder. Participants will receive either the drug or a placebo, and researchers will use brain scans and questionnaires to measure changes in mood and brain activity. The goal is to understand how psychedelics affect the brain in people with these conditions.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Ohio State University Department of Psychiatry

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.