MRNA vaccine takes on deadly brain tumors in first human trial
NCT ID NCT05938387
First seen Feb 27, 2026 · Last updated Jun 13, 2026 · Updated 16 times
Summary
This early-stage study tested an experimental mRNA vaccine called CVGBM in 37 people with a severe brain cancer (glioblastoma or a similar tumor). Participants received the vaccine after surgery and radiation. The main goal was to check safety and find the right dose. The vaccine aims to train the immune system to fight remaining cancer cells.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU de Liège
Liège, Belgium
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Erasmusmc Cancer institute
Rotterdam, South Holland, Netherlands
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Neurosurgical Clinic at the LMU Munich
München, Germany
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Universitair Ziekenhuis Brussel - PPDS
Brussels, Belgium
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Universitatsklinikum Leipzig
Leipzig, Saxony, Germany
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University Clinic Heidelberg
Heidelberg, Baden-Wurttemberg, Germany
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University Clinic Regensburg
Regensburg, Bavaria, Germany
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University Hospital Essen
Essen, North Rhine-Westphalia, Germany
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Universitätsklinikum Bonn
Bonn, North Rhine-Westphalia, Germany
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Universitätsklinikum Frankfurt
Frankfurt am Main, Hesse, Germany
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Universitätsklinikum Freiburg
Freiburg im Breisgau, Baden-Wurttemberg, Germany
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Universitätsklinikum Tübingen
Tübingen, Baden-Wurttemberg, Germany
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Universitätsmedizin Mannheim
Mannheim, Baden-Wurttemberg, Germany
Conditions
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