MRNA vaccine takes on deadly brain tumor in first human test

NCT ID NCT05938387

First seen Feb 27, 2026 · Last updated Apr 29, 2026 · Updated 9 times

Summary

This early-stage study tested a new mRNA vaccine (CVGBM) in 37 people with a fast-growing brain cancer called glioblastoma. Participants received the vaccine after surgery and radiation. The main goal was to check safety and find the best dose, while also watching for any signs that the vaccine might help control the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU de Liège

    Liège, Belgium

  • Erasmusmc Cancer institute

    Rotterdam, South Holland, Netherlands

  • Neurosurgical Clinic at the LMU Munich

    München, Germany

  • Universitair Ziekenhuis Brussel - PPDS

    Brussels, Belgium

  • Universitatsklinikum Leipzig

    Leipzig, Saxony, Germany

  • University Clinic Heidelberg

    Heidelberg, Baden-Wurttemberg, Germany

  • University Clinic Regensburg

    Regensburg, Bavaria, Germany

  • University Hospital Essen

    Essen, North Rhine-Westphalia, Germany

  • Universitätsklinikum Bonn

    Bonn, North Rhine-Westphalia, Germany

  • Universitätsklinikum Frankfurt

    Frankfurt am Main, Hesse, Germany

  • Universitätsklinikum Freiburg

    Freiburg im Breisgau, Baden-Wurttemberg, Germany

  • Universitätsklinikum Tübingen

    Tübingen, Baden-Wurttemberg, Germany

  • Universitätsmedizin Mannheim

    Mannheim, Baden-Wurttemberg, Germany

Conditions

Explore the condition pages connected to this study.