Can turmeric and grape compounds help slow ALS?
NCT ID NCT04654689
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 2 trial tested a combination of liposomed curcumin (from turmeric) and resveratrol (from grapes) plus a drug called G04CB02 in 90 people with ALS. The goal was to see if this mix could improve muscle function, thinking, and inflammation over 2 months of treatment. Participants were randomly assigned to get the active treatment or a placebo, and were followed for 4 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- liposomed curcumin and resveratrol plus G04CB02
- What this could lead to
- If it works, this could point toward a way to slow ALS progression and reduce inflammation.
- What could go wrong
- This is a small, early-phase trial with only 90 participants. The results may not apply to all ALS patients, and the supplements may not show clear benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
José Enrique de la Rubia Ortí
Valencia, Valencia, 46007, Spain
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