Can turmeric and grape compounds help slow ALS?
NCT ID NCT04654689
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 2 trial tested a combination of liposomed curcumin (from turmeric) and resveratrol (from grapes) plus a drug called G04CB02 in 90 people with ALS. The goal was to see if this mix could improve muscle function, thinking, and inflammation over 2 months of treatment. Participants were randomly assigned to get the active treatment or a placebo, and were followed for 4 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
liposomed curcumin and resveratrol plus G04CB02
What this could lead to
If it works, this could point toward a way to slow ALS progression and reduce inflammation.
What could go wrong
This is a small, early-phase trial with only 90 participants. The results may not apply to all ALS patients, and the supplements may not show clear benefit.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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José Enrique de la Rubia Ortí
Valencia, Valencia, 46007, Spain