New hope for Tough-to-Treat colon cancer: experimental drug shows promise in early trial

NCT ID NCT05513742

First seen Apr 18, 2026 · Last updated Apr 28, 2026 · Updated 2 times

Summary

This study tested an experimental drug called CTX-009 in 49 adults with metastatic colorectal cancer that had worsened after two or three prior chemotherapy treatments. The goal was to see if the drug could shrink tumors or stop them from growing. Researchers measured how many patients had their tumors shrink or stabilize, and for how long. This is a phase 2 trial, meaning it's still early, but results could lead to a new option for people with advanced colon or rectal cancer.

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Contacts and locations

Locations

  • Florida Cancer Specialists & Research Institute - North

    St. Petersburg, Florida, 33705, United States

  • Florida Cancer Specialists & Research Institute - South

    Fort Myers, Florida, 33916, United States

  • Genesis Cancer and Blood Institute

    Hot Springs, Arkansas, 71913, United States

  • Mary Crowley Cancer Research

    Dallas, Texas, 75230, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • Zangmeister Cancer Center

    Columbus, Ohio, 43219, United States

Conditions

Explore the condition pages connected to this study.