New pill takes on advanced cancers: early trial begins

NCT ID NCT06717750

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests an experimental oral drug called CSCJC3456 in 102 people with advanced solid tumors that have not responded to standard treatments. The study aims to find a safe dose and check for any signs that the drug can shrink tumors. Participants take the tablet daily in one of several dose groups, and researchers monitor side effects and drug levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CSCJC3456 tablet

What this could lead to

If this drug proves safe and shows early signs of shrinking tumors, it could lead to a new treatment option for people with advanced solid cancers who have run out of standard therapies.

What could go wrong

This is a very early Phase I trial with only 102 participants. The main goal is safety, not effectiveness. Many cancer drugs that look promising in early testing fail in later, larger studies. Side effects are unknown and could be serious.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer colorectal cancer endometrial cancer gastric cancer hepatocellular carcinoma metastatic malignant neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of China Medical University

    RECRUITING

    Shenyang, Liaoning, 110001, China

    Contact