New pill takes on advanced cancers: early trial begins

NCT ID NCT06717750

Recruiting now Disease control Sponsor: Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests an experimental oral drug called CSCJC3456 in 102 people with advanced solid tumors that have not responded to standard treatments. The study aims to find a safe dose and check for any signs that the drug can shrink tumors. Participants take the tablet daily in one of several dose groups, and researchers monitor side effects and drug levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CSCJC3456 tablet
What this could lead to: If this drug proves safe and shows early signs of shrinking tumors, it could lead to a new treatment option for people with advanced solid cancers who have run out of standard therapies.
What could go wrong: This is a very early Phase I trial with only 102 participants. The main goal is safety, not effectiveness. Many cancer drugs that look promising in early testing fail in later, larger studies. Side effects are unknown and could be serious.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer colorectal cancer endometrial cancer gastric cancer hepatocellular carcinoma metastatic malignant neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED MALIGNANT SOLID TUMORS

Contacts and locations

Locations

Cancer Hospital Chinese Academy of Medical Sciences
RECRUITING

Beijing, Beijing Municipality, 100021, China
The First Hospital of China Medical University
RECRUITING

Shenyang, Liaoning, 110001, China

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