Freezing nerves may offer lasting relief from phantom limb pain

NCT ID NCT06071715

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a treatment called cryoanalgesia, which uses extreme cold to freeze nerves in the thigh, for people with phantom limb pain after an above-knee amputation. The goal was to see if a single freezing treatment could reduce pain better than a sham (fake) procedure. Twelve adults with daily moderate-to-severe phantom pain were enrolled and followed for up to 12 months.

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Conditions

The condition(s) this trial relates to.

Amputation, Traumatic Phantom Limb

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California San Diego

    La Jolla, California, 92037, United States

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