Freezing heart tissue to stop lethal rhythms: new trial launches

NCT ID NCT05675865

Ongoing Disease control Sponsor: Adagio Medical Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study tests a new device that uses extreme cold (cryoablation) to treat a fast, dangerous heart rhythm called sustained monomorphic ventricular tachycardia. About 206 adults with this condition will receive the freezing treatment. The goal is to see if it safely stops the abnormal rhythm without causing serious side effects.

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Conditions

The condition(s) this trial relates to.

arrhythmogenic right ventricular cardiomyopathy intrinsic cardiomyopathy ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SUSTAINED VT

Contacts and locations

Locations

Banner University Medical Center Phoenix

Phoenix, Arizona, 85006, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Hospital of University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Johns Hopkins University

Baltimore, Maryland, 21287, United States
McGill University

Montreal, Quebec, H4A 3J1, Canada
Medical Center of South Carolina (MUSC)

Charleston, South Carolina, 29403, United States
Montreal Heart Institute

Montreal, Quebec, H1T 1C8, Canada
Northwell Health- Staten Island University Hospital

Staten Island, New York, 10305, United States
Ohio State University

Columbus, Ohio, 43210, United States
Texas Cardiac Arrhythmia Research Institute (TCARF)

Austin, Texas, 78705, United States
University of California San Francisco

San Francisco, California, 94143, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States
Weill Cornell Medical Center

New York, New York, 10065, United States

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