Freezing heart tissue: new balloon trial for AFib patients
NCT ID NCT05905835
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This trial tests a new device called the Synaptic Cryoablation System, which uses a balloon to freeze small areas of the heart and correct irregular heartbeats in people with paroxysmal atrial fibrillation. 128 participants will receive the treatment and be followed for 12 months. The goal is to see if it safely stops abnormal heart rhythms and improves symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Synaptic Cryoablation System (a device that freezes heart tissue to correct irregular heartbeats)
What this could lead to
If successful, this could offer a new, effective option for controlling atrial fibrillation and reducing symptoms without long-term medication.
What could go wrong
This is an early-stage trial with only 128 participants, so results may not apply to everyone. Risks include procedure-related complications like heart damage or stroke.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Banner University Medical Center
Phoenix, Arizona, 85006, United States
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Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
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Christus Health Frances Hospital
Tyler, Texas, 75701, United States
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Dignity Health Arizona Research Enterprise
Phoenix, Arizona, 85006, United States
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Mercy General Hospital
Sacramento, California, 95819, United States
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Northwell Health - Lenox Hill Hospital
New York, New York, 10075, United States
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St. Bernard's Heart & Vascular
Jonesboro, Arkansas, 72401, United States
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St. Luke's Mid America
Kansas City, Missouri, 64111, United States
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VCU Pauley Heart Center
Richmond, Virginia, 23298, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States