New study aims to unlock Alzheimer's secrets by tracking brain changes over time

NCT ID NCT07611396

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

The CROWN-I study is an observational research project involving 160 people with Alzheimer's disease or mild cognitive impairment. Participants will provide samples and undergo assessments over time to help researchers understand the molecular and genetic features that distinguish different subtypes of the disease and predict how it will progress. This study does not test any treatment, but aims to gather knowledge that could inform future therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help identify different types of Alzheimer's disease and predict how it will progress, potentially guiding future treatments.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly help participants. It may not find clear patterns, and results may take years to impact patient care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Capital Neurology

    RECRUITING

    Germantown, Maryland, 20876, United States