New hope for rare Kidney-Blood disease: crovalimab trial shows promise
NCT ID NCT04861259
First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 29 times
Summary
This study tests a new medicine called crovalimab for people with a rare disease called atypical hemolytic uremic syndrome (aHUS), which causes blood clots and kidney damage. The trial includes 83 adults and teens who receive the drug to see if it can control the disease and improve kidney function. Participants must be up to date on certain vaccines to join.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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A.O. Universitaria S. Martino Di Genova
Genoa, Liguria, 16132, Italy
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All India Institute Of Medical Sciences (AIIMS)
New Delhi, National Capital Territory of Delhi, 110029, India
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Complejo Hospitalario Universitario A Coruña (CHUAC)
A Coruña, 15006, Spain
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Del- Pesti Centrumkorhaz- Szent Laszlo Korhaz Telephely
Budapest, 1097, Hungary
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Emory Children's Center
Atlanta, Georgia, 20010, United States
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome, Lazio, 00168, Italy
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Hopital Lapeyronie
Montpellier, 34295, France
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Hopital Tenon
Paris, 75970, France
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Hospital Clinic i Provincial
Barcelona, 08036, Spain
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Hospital General de México
Distrito Federal, Mexico CITY (federal District), 06726, Mexico
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Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
Monterrey, Nuevo León, 64460, Mexico
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Hospital Universitario Virgen del Rocío
Seville, 41013, Spain
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Hospital das Clinicas - FMUSP
São Paulo, São Paulo, 05403-000, Brazil
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Hospital de Especialidades Puerta de Hierro S.A de C.V.
Zapopan, 45116, Mexico
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Hôpital Robert Debré
Paris, 75019, France
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Instituto Nacional de Ciencias
Mexico City, Mexico CITY (federal District), 14080, Mexico
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Instytut ?Centrum Zdrowia Matki Polki
Lodz, 93-338, Poland
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Istanbul University Istanbul Medical Faculty
Istanbul, 34390, Turkey (Türkiye)
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Klinik II für Nephrologie, Rheumatologie, Diabetologie und Allgemeine Innere Medizin
Cologne, 50937, Germany
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Klinik für Nephrologie des Universitätsklinikum Essen
Essen, 45147, Germany
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Kocaeli University Medical Faculty
Kocaeli, 41380, Turkey (Türkiye)
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Malatya Park Hospital
Malatya, 44330, Turkey (Türkiye)
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Medanta-The Medicity
Gurgaon, Haryana, 122001, India
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Medizinische Hochschule Hannover
Hanover, 30625, Germany
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Nagoya University Hospital
Aichi, 466-8560, Japan
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Necmettin Erbakan University Meram Medical Faculty
Konya, 42080, Turkey (Türkiye)
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Peking University First Hospital
Beijing, 100034, China
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Rabin Medical Center
Petah Tikva, 49100, Israel
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Rambam Medical Center
Haifa, 3109601, Israel
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Saitama Medical University Hospital
Saitama, 350-0451, Japan
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Santa Casa de Misericordia
Belo Horizonte, Minas Gerais, 30150-221, Brazil
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Sheba MC
Ramat Gan, 52621, Israel
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The Ohio State University Wexner Medical Center
Columbus, Ohio, 43212, United States
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The University of Tokyo Hospital
Tokyo, 113-8655, Japan
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UPECLIN Hospital das Clinicas da Faculdade de Medicina de Botucatu
Botucatu, São Paulo, 18618-686, Brazil
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UT Health Science Center
San Antonio, Texas, 78229, United States
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UZ Leuven Gasthuisberg
Leuven, 3000, Belgium
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Univ of CA San Francisco
San Francisco, California, 94143, United States
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Universitätsklinikum Essen
Essen, 45122, Germany
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Vancouver General Hospital
Vancouver, British Columbia, V5Z 2S3, Canada
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Washington University
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.